By Terry F. Davies
In A Case-Based Guide to Clinical Endocrinology, Second variation, a popular crew of exclusive clinicians once back offers stimulating instruction and insights into a wide selection of endocrine topics, teaching readers modern administration of the stipulations defined and offering exact access into the literature. Importantly, a number of the very important components within the present curriculum for scientific endocrine education as suggested via the organization of application administrators in scientific Endocrinology, Diabetes and Metabolism are coated during this textual content. completely up-to-date, this new version not just covers new remedy methods but in addition emphasizes the most recent investigative advances in either imaging and molecular diagnostics. to enhance studying and retention of information, a question-based strategy is utilized in some of the case reports. scholars, citizens, fellows, and practitioners will locate this connection with be a good approach to overview their understanding and elevate their skills and abilities in sufferer research and administration. a useful contribution to the sphere, A Case-Based Guide to Clinical Endocrinology, Second Edition, deals a similar comprehensive volume of thought-provoking case-studies that made the 1st variation of important value to all clinicians who deal with sufferers with endocrine disorders.
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Extra resources for A Case-Based Guide to Clinical Endocrinology
Treatment of adrenocorticotropin-dependent Cushing’s syndrome: a consensus statement. J Clin Endocrinol Metab. 2008;93:2454–62. G. Yedinak et al. 3. Boscaro M, Arnaldi G. Approach to the patient with possible Cushing’s syndrome. J Clin Endocrinol Metab. 2009;94:3121–31. 4. Colao A, De Block C, Gaztambide MS, Kumar S, Seufert J, Casanueva FF. Managing hyperglycemia in patients with Cushing’s disease treated with pasireotide: medical expert recommendations. Pituitary. 2014;17(2):180–6. 5. Colao A, Petersenn S, Newell-Price J, Findling JW, Gu F, Maldonado M, et al.
Further questioning revealed; oily skin, more abundant skin tags, profuse sweating, and the return of more frequent and more severe headaches. A physical exam revealed typical signs indicative of acromegaly: large hands and large wide feet, significant prognathia, frontal bossing, a large tongue, and several gaps between his teeth. Pulmonary and cardiac auscultations were unremarkable. Examination of his skin showed multiple skin tags in his axilla, which demonstrated acanthosis nigricans. Visual field (VF) testing by confrontation suggested bitemporal field deficits.
At this time, medical therapy was pursued to control her hypercortisolemia since she was reluctant to consider BLA. Radiation treatment was also discussed, but in the absence of a target tumor seen on MR images, desire for fertility and patient reluctance, this was postponed as a possible third-line therapy. The initial agent was ketoconazole. While not approved in the USA for hypercortisolemia, it is a well-known off-label treatment option in the absence of appropriate alternative treatments. Ketoconazole acts to impair steroid hormone synthesis by blocking adrenal 11 beta-hydroxylase.
A Case-Based Guide to Clinical Endocrinology by Terry F. Davies